The Swiss Medicine & Pharmaceuticals,
Consultation In Applied Research Using Ai & ML @ Institute Of Bio Medical Engineering, Applied Research Using BigData in Public Health
- Vitors 5600/Advia Centaur Xpt/Immulite 2000 XPi/Liaison / Maglumi 2000 Plus Random Access Immunoassay Analyzer,
- Urised 3 and Labumat Urine Analyzer
- Atellica Siemens Automated Analyzer
- Vitros ECI /Advia Centaur XP/Architect I 1000 SR/Liaison Random Access
- Checked Manually
Non Prejudicial Disclosure, Intellectual Property: Solution Design Using Ai in Bio Medical Engineering,
Date: March 19 , 2022
Thretre: Development Country Applied Research: Ai in Public Health Care
Contagious and Infectious Disease
Laboratory Medical Science & Engineering - Blood Diseases Research and Infections,
Released: Date: Jun 23rd 2022
Case 28: Rare Blood Disease, Toxic Anemia, Liver Disease,
CKD, Blood Disease analysis:Our patient is a 86 yr old male, deteriorating diabetics patient wiht type 2 end state whose insulin injection does increases from 1 to 3 dose each time before meal, a day. Due to increase in blood sugar reading which went up 14-18.0 after dose increase the average reading was 3.4- 6.5. We moves to test /research to retain status in Serology, why increase in dose up to 3 dose pre-meal was needed. We retained data in one day interval of frequency for, complete blood glucose test, of 3-4 months data as collected.
A Hematology report states:
Hemoglobin results 11.7 g/dl
ESR( Westergen) 62 mm/ist hr way over than (0-12) range demonstrating blood infection.
Total RBC ucnt 13600 over (4000-11000c/mm) range.
Differential count:
Neutrophils 80% over (40-75%)
Lymphocytes 16% below (20-50%)
Monocytes 02(02-08%) Eosinophils 02( in normal range (01-06)
Basophil 00(00-01% normal range
Other tests:
Platelet count 254000 /cumm within normal (150000-450000 /cumm
RBC count 4.47 m/ul close to male normal range 4.5-6.5
HCT/PCV 36.1 % below male normal range 40-54%
MCV 80.8 fl normal range 76-94 fl
MCH 26.2 pg below normal range 27-32 pg
MCHC 32.4 g/dl within normal range 29-34g/dl
ESR Westergreen method 62 mm/1 hr which is much more over than 0-10 for male.
BLOOD FILM: reveals neutrophilic Leukocytosis with High ESR: specimen within normal platelet
RBC Anisocytosis and Anisochromia
WBC Mature and shows feature of Neutrophilic Leukocytosis
Immunological report:
Serum Ferrin 974.50 ng/ml which is way over the normal range for male 32-501 ng//ml
Serological Report:
C-Reactive Protein 12 mq/L which is over normal range 6.0 mg/l
Biochemical report:
S.Phosphorus (PO4) within normal range 3.3 mg/dl normal 2.7-45
S.Iron 56 uq/dl for male within normal range.
S. Urea 24 mg/dl (10-40)
Plasma Globose Random 12.2 mmol/L ,over normal range of <7.8
S.Albumin 27 g/L (35-50 normal)
HbA1C 6.6 % where reference range is less than 6.0
S.Creatinine 14.4 mg/dl which is over male -range 06-1.3
S.Uric acid 6.5 mg/dl normal range for Male 3.4-7.0
S.Calcium 6.6 mg/dl normal range 8.8-10.6
SGPT (ALT) 76 which is over normal rang e42 U/L
Serum Electrolytes:
S.Sodum 138 within normal range 135-150 mmol/L
S.potassium 3.4 mmol/L belwo normal range 3.5-5.0
S.Chloride 101 mmol/L normal range 94-110
TIBC 174 uq.dl which is below normal range 274-494
Stool Examination:
OBT - negative.
Application of ML, Ai Research Bio Medical Engineering, Case Study Analysis:
Research & Development - Liver , kidney, blood Cancer, TF, Blood Cell count and Activation Status for B , T, NK -Lymphocyte
Damage Analysis:
SUMMARY:
We conclude that the patient suffers for liver disease due to SGPT increase in chronic diabetics status with low Lymphocytes which is generated from bone marrow and thymus, indicate the patient is in infection.
The PCV/HCT reading shows blood disorder (with high ESR) or kidney failure or related issue. Nutritional Deficiencies of iron or vitamins, inflammatory or kidney-related conditions like rheumatoid arthritis or kidney failure could take place also. The patient suffers for CKD. Hemolysis, or the disease in which RBCs are destroyed; the immune system will result in further result in many damages or inherited abnormalities in the RBCs.
Patient suffers, mild bone marrow disorder, myelodysplastic, this could have resulted in this low PCV. Low MCH reading show iron deficiency, anemia for producing less hemoglobin. Low MCV indicates that RBC are smaller than normal, microcytic anemia is observed. Within range, the reading of Mean corpuscular hemoglobin concentration (MCHC) shows of the average amount of hemoglobin in a single red blood cell (RBC) ,i.e volume of the RBC cell in range.
The Low TIBC count shows transferrin protein does not carry iron in blood properly. Cirrhosis the scarring (fibrosis) of the liver may have caused by long-term liver damage , the end stage. It could happen to patients after hepatitis infection.
The negative (OBT)Fecal Occult Blood Test) shows -ve, as a result no bleeding, or cancer or polyp growth in colon is found, in the inner wall of rectum. No need of colonoscopy.
C-Reactive Protein, (hs-CRT test not available ) test indicates the patient has a serious heath condition that causes inflammation to protect tissues and heal from an injury, infection, or other disease. The Inflammation is acute .
The Microscopic examination of presence of Pus cell (1-3) /HPF, and epithelial cell (2-3) HPF proves , activated and accumulated white blood cell in response to infection in the body.