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The Swiss Medicine & Pharmaceuticals,

Consultation In Applied Research Using Ai & ML @ Institute Of Bio Medical Engineering, Applied Research Using BigData in Public Health




    Non Prejudicial Disclosure, Intellectual Property: Solution Design Using Ai in Bio Medical Engineering,
    Date: Jun 14, 2023
    Thretre: Development Country Applied Research: Ai in Public Health Care

    Contagious and Infectious Disease
    Laboratory Medical Science & Engineering - Cancer, HIV, Diabetes, HPV Research and Heredity Blood, Water Borne Diseases


    Case 30:CKD- Diagnosis:



    CKD:

    our patient is a 91 year old male, who is the contributor of the ample, suffers from CKD.

    Case history:

    Acute problem : AKI on CKD, Septicaemia due to Pneumonia,Fracture Neck of Femer(left).
    Co morbid Illness:Type 2 Diabetes Mellitus ,Hypertension,IHD(S/P-PCI -2006),BEP,Renal Anemia.
    No general allergy or drug allergy known.


    Presenting Complaints:

    Several times vomiting for last 2 days
    H/O fall 17 days back
    Pain and can not walk following fall
    General Examination: Patient was ill looking, P-98/min regiar ,BP-120/60 mmHg; Temp-99F,
    Sp02- 97% in room air.

    Systematic examination : Heart -S1+S2+0 Lings- Vesicular with bilateral crepitation,distended, soft, non tender, other systemics
    examinations revels normal
    Investigation done:all investigation reports are supplied to the patient.
    Clinical Course: After admission the patient was evaluated properly and managed conservatively.He was suffering for chest infection.
    Urine culture and blood culture were sent to find infection. Stool OBT was positive but evaluation could not be done. Patient in unstable condition.


    Diet: Diabetic Renal
    Fluid: 2 L/day
    Protein: 40 gm/day(high) we adopt the following tests:

    .

    We used

  • Vitors 5600/Advia Centaur Xpt/Immulite 2000 XPi/Liaison / Maglumi 2000 Plus Random Access Immunoassay Analyzer,
  • Urised 3 and Labumat Urine Analyzer
  • Atellica Siemens Automated Analyzer

  • Vitros ECI /Advia Centaur XP/Architect I 1000 SR/Liaison Random Access
  • Checked Manually


    a) Bio chemistry Report


    Lipid Profile
    sample(serum)


    Cholesterol (total) 193 mg/dL Desirable Level : <200.00
    Borderline High 200.00 -239.00
    High Cholesterol :>=240.00

    HDL –Cholesterol 33.00 mg/dL Desirable : < 100.00
    Borderline High : 130.00 -159.00
    High 160.00 -189.00

    LDL – Cholesterol 124.00 mg/dL Desirable :< 100.00
    Borderline High :130.00 – 159.00
    High 160.00 – 189.00


    Triglycerides 226.00 mg/dL Desirable :< 150.00
    Borderline high : 150.00 – 199.00
    High : 200.00 – 499.00



    ALT (SGPT) 20 U/L Male: Upto 41
    Female: Upto 33

    AST(SGOT) 19 U/L Male: Up to 40
    Female: up to 33

    sample(serum)

    Calcium 9.60 mb/dL Adult: 8.80 -10.60
    Neonates( 0- 10 days) 7.60 – 10.40
    Children ( 2- 12 yrs) 18.80 – 10.80


    Inorganic Phosphate(PO4) 4.97 mg/dL Adults 2.50 – 4.50
    Children :

    1-30 days : 3.90 – 6.90 1-
    12 mon- 3.50 – 6.60 1-
    3 yrs - 3.10 – 6.00
    4 yrs – 6 yrs 3.30 – 5.60
    7-9 yrs 3.00 – 5.400
    10 -12 yrs 3.20 -5.70
    13-15 yrs 2.90 – 5.10


    Creatinine 2.13 mg/dL Adults:
    Males : 0.70 -1.20
    Females: 0.50 – 0.90
    Children

    Neonates: 0.24- 0.85


    Urea 104.69 mg/dL 16.,60 -48.50 sample (serum)
    Uric Acid 10.41 mg/dL Male 3.50- 7.20
    Female: 2.60 – 6.00









 

 


    Application of ML, Ai Research Bio Medical Engineering, Case Study Analysis:



    Research & Development - Bio Medical Engineering - Imaging Sciences




    Clinical Pathology Report

    Urine Routine Examination

    Physical Examination

    Quantity 25mL (approx)
    Color straw
    Appearance Clear
    Sediment Nil


    Chemical Examination


    Urine for Specific Gravity 1.010
    Reaction (PH) 5.0
    Albumin +
    Sugar +++ Bilirubin Nil
    Urobilinogen Normal
    Nitrite Negative
    Ketone Nil



    Microscope Examination

    Epithelial Cells 1-2 /HPF
    RBC Nil/HPF
    Pus Cells 0-2/HPF
    Cellular Cast Nil /LPF
    Granular Cast Nil/LPF
    Hyaline Casts Nil
    Calcium Oxalate Nil
    Triple Phosphate Nil
    Uric Acid Nil
    Amorphous Phosphate Nil





    Differential Count

    Neutrophils 57% <75
    Lymphocytes 38% <40
    Monocytes 03% <10
    Eosinophils 02% <6
    Basophils 00% <1.0


    Platelet Count


    Total Platelet count 30100 /Cmm <450000
    MPV 11.5 fL 8.0-9.5





    c) Electrolytes sample(serum)

    Sodium (Na) 136.00 mmoL/L 136.0- 145.0
    Potassium (K) 4.58 mmoL/L 3.50 -5.10
    Chloride(Cl) 102.00 mmoL/L 98.00 – 107.00
    Carbondioxide (CO2) 24.00 mmol/L 24.00 -30.00
    Bicarbonate (HCO3) 22.00 mmol/L 22.00 – 28.00

    Fasting Plasma Glucose 5.88 mmol/L Adult: 4.11 – 6.05 (Sample Plasma Fluoride)
    corresponding Urine Sugar with FPG +++



    Immunology Report

    Hb A1c 8.20 % sample: whole blood



    b)Hematology:

    Hematology Report:

    CBC and ESR

    Total Count

    White Blood cell 14.19 K/microL 4.0 – 11.00
    Neutrophils 10.78 K/microL 2.0-7.0
    Lymphocyte 2.41 K/microL 1.00 -3.00
    Monocyte 0.71 K/microL 0.20- 1.00
    Eosinophil 0.28 K/microL 0.02 – 0.50

    Differential Leucocyte Count

    Neutrophil% 76 % 40.00-80.00
    Lymphocyte % 17 % 20.00 – 40.00
    Monocyte% 05 % 2.00 -10.00
    Eosinophil% 02 % 1.00 – 6.00
    Basophil% 00 % <2.00
    Red blood Cell 4.42 million/microL 4.50 -5.50
    Haemoglobin 11.00 g/dL 13.00 -17.00
    HCT 35.50 % 38.90 – 50.90
    MCV 80.3 fl 81-94
    MCH 24.9 pg 27 – 33
    MCHC 31.0 g/dL 33 -37
    RDW-CV (%) 14.6 % 12 -14
    Platelets 255 k/microL 150-410
    MPV 11.60 fl
    PCT 0.29 %
    PDW 13.80 fl
    ESR 124 mm/hr


    Rx and Medication:

    Note: A3iNet is a hybrid Deep Learning HDNN, Neural Network Systems, applied to Complex Systems Of Systems' Scientific and Industrial Systems Integration as Solution enforced with Ai for Large Scale Enterprise Integration, LSSI, developed by Swedish World Wide & Aerovition Digital Inc..











 




 

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